案例概述 41 岁女性患者，初诊左侧乳腺浸润性导管癌 cT3NxM0，IIIC 期，LuminalA 型（HER2 IHC 2+/FISH-），接受新辅助化疗、左侧乳腺癌改良根治术 ...

HER2 is one of 21 genes included in OncotypeDX ... says that for certain patients, the immunohistochemistry and FISH results never agree. “Just because you have a change in gene copy number ...

Future Oncol. 2015;11(7):1023-1026. Tumor-negative breast cancers misclassified as HER2 negative by IHC (0 or 1+) could therefore be reclassified by FISH, with a remarkable impact on medical ...

The analysis was performed on independent study sets of HER2-positive and negative/low breast cancers, already analyzed by central immunohistochemistry (IHC) and FISH testing. Phospho-HER2 and ...