Figure 5: Multiple roles for NFATs in the heterotypic interactions of the tumour microenvironment. In the past few years evidence has accumulated that points to a key role for NFAT transcription ...
Van Meir's research examines how genetic alterations and hypoxia induce changes in cell biology that promote tumor formation with particular emphasis on heterotypic cell-cell signaling, including ...
The main hypothesis is that ferumoxytol will reduce immunosuppressive, tumor-promoting TAMs. This reduction in TAMs is expected to increase breast cancer sensitivity to radiotherapy by both disrupting ...