With the final step in HIF pathway established, scientists began to explore ways to utilize it. Because the hypoxia response is present across all tissues and cell types, the HIF pathway drives ...

Clear cell RCC is almost universally associated with HIF-2a dysregulation as a result of genetic abnormalities in the VHL pathway. This creates a situation of pseudohypoxia and the abnormal ...

A small panel of circulating biomarkers may reliably distinguish hypertrophic cardiomyopathy (HCM) from similar conditions that cause left ventricular hypertrophy (LVH), researchers found. From ...