Two recent reports show that the co-chaperone CHIP mediates ubiquitin-dependent degradation of substrates bound to heat-shock protein 70 (Hsp70) and/or Hsp90. Figure 1: Models for the involvement ...

许多热休克蛋白具有分子伴侣活性。按照蛋白的大小，热休克蛋白共分为五类，分别为HSP100, HSP90, HSP70, HSP60以及小分子热休克蛋白（small Heat Shock Proteins, sHSPs)。热休克蛋白最引人注目的是其分子伴侣作用，在整个细胞中促进蛋白质的合成和折叠。此外，有研究 ...

Hsp70-Hsp90 organizing protein; TRiC: tailless complex polypeptide 1 ring complex; Hsp90: heat-shock protein 90; Aha1: Activator of Hsp90 ATPase.

The answer lies in the molecular chaperone heat shock protein 90 (Hsp90), according to a recent report in Current Biology. ...Hsp90 inhibitors could induce a switch from yeast to filamentous ...

Backe, and Mehdi Mollapour from SUNY Upstate Medical University and New York VA Health Care in Syracuse, New York, discuss ...

We determined the structure and function of Heat Shock Protein 90 (Hsp90), a molecular chaperone which is critical for the growth and survival of cancer cells. Photo: Jan Chlebik for the ICR We worked ...

It's an often-used phrase in bike media, but a tyre upgrade is about the best bang for your buck as far as upgrades go. New bikes are often specced with cheaper tyres in order to hit a price point ...

Launched in early 2023, the Pirelli P Zero Race 4S TLR is the brand’s all-season road tyre designed to be used throughout winter without sacrificing as much rolling resistance and speed as more ...