Hsp90 has a role in nearly every cellular function ... Trap1 translocated to the mitochondria. Inhibition of Trap1 at this stage markedly affected the prestarvation response and inhibited ...

Surprisingly, Kang et al. 2 found that HSP90 (whether HSP90α, HSP90β or both is not clear) localized to the mitochondria of tumor cells but not normal cells. Similarly, TRAP-1 was more abundant ...