研究者从iHMP宏基因组测序数据中挖掘发现了大量类病毒，发现存在全新的一大类类病毒序列，命名为obelisks。研究者发现obelisk ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific ... To fortify the case for fungal tRNA ligase as a drug target, we need to understand the properties of Trl1 ...

▎药明康德内容团队编辑  我们知道，人类只有2%的基因真正负责编码蛋白质，而处于非编码区的其余98%一度被视作“垃圾DNA”。但近些年来，这些非编码区域在生命活动中的作用逐渐被揭开。尽管不编码蛋白质，但这些非编码区域也会转录为RNA，其中就包括数千个 ...

Not junk, after all Using CRISPR-Cas13 to edit RNA and avoid off-target activity, the researchers systematically profiled nearly 6,200 gene pairs of long noncoding RNAs (lncRNAs) and nearby ...

Looking ahead, the research team plans to expand their work to study how these RNA processes operate in other crops and in ...

We can already tinker with human DNA to treat diseases. But being able to edit RNA allows for even more precision – and fewer ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA ...

复旦大学生物医学研究院和附属肿瘤医院黄胜林团队在期刊《Cell Reports》上发表了题为“RNA splicing junction landscape reveals abundant tumor-specific trans in human ...

A personalised vaccine for the aggressive and fatal brain cancer glioblastoma has shown encouraging signs of efficacy in its first human trial ... The team’s RNA-LNP approach – described ...