Obviously, this is not an option in humans. “The only thing you can do for human iPSCs is take that cell line and put it into a teratoma assay in a mouse, and ask if the tumor tissues that form ...
But the impact of iPSCs on drug discovery has been frustratingly modest. “Everyone thought that stem cells were going to give us the human cell models that we required to make better drugs ...
Human iPSCs are a new type of pluripotent cell reprogrammed from patient or donor cells into versatile stem cells that can become any cell type. These iPSC-derived cells, which retain disease ...
Human induced pluripotent stem cells (iPSCs) have a great potential for scientific and medical applications. They are used in research laboratories to model human diseases, helping to uncover ...
derivation of functional dopamine neurons from various cell sources including human ES cells, based on the strategy of cell replacement therapy to parkinson’s disease, and ii) specific gene functions ...
The Purdue Institute for Integrative Neuroscience (PIIN) Cell Engineering Core was established to facilitate stem-cell-related research for the Purdue community by providing induced pluripotent stem ...
So, some scientists use human induced pluripotent stem cells (iPSCs) to produce hepatocyte-like cells (HLCs) that can be used as model systems for the development of new therapies for liver disease.