Conditional gene targeting based on excision or inversion ... construct and the loxP-flanked target sequences. In the case of inducible systems, one must also examine recombination before and ...

This useful study examines the function of the rnc gene, which encodes the RNase III ribonuclease, as it relates to virulence of Salmonella Enteritidis. The authors demonstrate that the rnc gene is ...

Here’s how it works. Scientists have discovered a gene variant that could make some parents more likely to have girls than boys. In the new study, researchers analyzed the genomes of around ...

Oct. 28, 2024 — Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical ...

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...

Now, Sodhi and his fellow researchers have identified the accumulation of a hypoxia-inducible factor 1-alpha (HIF-1-alpha), ...

We recently found that unlike the rhesus macaque, the primary macaque species used for SIV-AIDS studies, the pigtailed macaque is susceptible to HIV-1 infection mainly because it does not express a ...

To improve long-term persistence and reduce the risk of immune rejection, researchers are exploring ways to diminish the ...

And, despite the pandemic, 2020 was a landmark year for the 24-year-old, from County Durham, who became the first person in the UK to receive a revolutionary new gene therapy on the NHS.

Participants were broken into two cohorts. The first cohort received one of three doses of PCRX-201. The second cohort received concurrent pretreatment with an intraarticular corticosteroid ...

Gene Park is a reporter for The Washington Post, covering video games and gaming culture. He joined The Post in 2015 as audience editor, and is a former reporter in the West Coast and Pacific region.