Marketed under the brand name Arava among others, the drug is approved by the U.S. Food and Drug Administration (FDA) and ...

This study investigated, for the first time, the efficacy and safety profile of leflunomide 20mg daily in ambulatory RA patients in typical settings. This is of importance, as the existing body of ...

Mitochondria have long been known as the tiny organelles that act as the battery packs inside our cells while also serving as internal sensors and communicators.

Leflunomide is the only nonbiologic DMARD developed specifically for the treatment of RA. It is an isoxazole derivative and its active metabolite, teriflunomide (formerly known as A77 1726), acts ...

Leflunomide is largely considered to be a second-line treatment option for rheumatoid arthritis (RA). Those who fail to respond, tend to progress to treatment with expensive biological agents ...

Researchers in the Netherlands therefore evaluated another DMARD, leflunomide, effective in psoriatic arthritis and rheumatoid arthritris, in a double-blind, randomized, placebo-controlled trial ...