Subset analysis of FASCINATE-2 Phase 2 trial demonstrated denifanstat improved fibrosis in difficult-to-treat MASH patients ...

The researchers identified a key biological pathway involving TGFβ, a protein linked to the immune system, which when blocked ...

Carisma Therapeutics Inc. (CARM) presented promising preclinical data on engineered macrophages for treating liver fibrosis at the ...

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality ...

A new study highlights how signals from the liver to the brain influence eating patterns tied to our circadian rhythms.

People who work the nightshift or odd hours and eat at irregular times are more prone to weight gain and diabetes, likely due ...

HMGB1's interactions with its primary receptors, RAGE and TLR4, are essential to its role in liver disease. Upon binding, ...

The liver communicates with the brain to regulate eating patterns, potentially helping those with disrupted schedules to ...

Learn about HMGB1's crucial role in liver diseases, its pathways and therapeutic potential that can treat liver diseases.

The aging and failure of cells that occurs when the liver is damaged can spread to other organs, a new study shows.

People who work the nightshift or odd hours and eat at irregular times are more prone to weight gain and diabetes, likely due to eating patterns not timed with natural daylight and when people ...