The endomembrane system was first discovered in the late 1800s when scientist Camillo Golgi noticed that a certain stain selectively ... The ER, Golgi apparatus, and lysosomes are all members ...

An experienced microscopist, Novikoff was able to obtain the first electron micrographs of the new organelle from samples of partially purified lysosomes. Using a staining method for acid ...

These observations open the door to more in-depth investigations looking into a potential mechanistic link between TMEM106b aggregation and pathological processes in neurodegeneration,” Rothstein ...