The answer lies in the molecular chaperone heat shock protein 90 (Hsp90), according to a recent report in Current Biology. ...Hsp90 inhibitors could induce a switch from yeast to filamentous ...

We determined the structure and function of Heat Shock Protein 90 (Hsp90), a molecular chaperone which is critical for the growth and survival of cancer cells. Photo: Jan Chlebik for the ICR We worked ...

They made a striking observation. “We were expecting to see maybe neutrophils or T cells, but the amount of macrophages we saw in the samples was huge,” Marichal said. “They are not normally present ...

These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...

There is evidence that lower doses may be equally effective, especially in patients with less severe edema. [10] If beneficial, neurological improvement can be expected within 48 h with this ...

A key factor in the complex repair process is the body's immune response, particularly the role of macrophages, which are immune cells that play a crucial role in inflammation following joint injury.

Therefore, we assume that once MOF nanoplatforms have been synthesized and one of the three substances – red blood cell membranes, cancer cell membranes or macrophage membranes – has been ...

Future Virology. 2013;8(6):561-573. Apoptosis is an effective mechanism to destroy virus-infected cells. Central to this process is the interaction of FADD and procaspase-8. [58] During TNFR-1 ...

HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy ... Cutaneous head and neck melanoma in OPTiM, a randomized phase 3 trial of talimogene laherparepvec versus ...