Normally, pro-inflammatory (M1) macrophages dominate the site of injury early on, and are subsequently replaced by reparative (M2) macrophages. M2 macrophages, typically activated with IL-4, may ...
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'If you don't have inflammation, then you'll die': How scientists are reprogramming the body's natural superpowerHe and others have found there are actually two types of macrophages: a damaging inflammatory type, dubbed M1, and a second type, called M2. His research in mice found that this second type turned off ...
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Study reveals how inflammatory immune cells enhance prostate cancer resistanceThe study examined the impact of factors promoting inflammation in a tumor microenvironment ... Researchers focused ...
Department of Physiology, Harold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, United States ...
Carisma Therapeutics is developing a unique, differentiated immuno-oncology (IO) treatment for solid tumors based on chimeric antigen receptor macrophages ... a pro-inflammatory M1 phenotype ...
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