Treating life-threatening bloodstream infections in combat situations is challenging, especially when the pathogen ...

Some supplements contain natural lectin blockers, such as N-acetyl glucosamine (NAG) and D-mannose, while others use synthetic compounds like polyphenols and sialic acid. It’s also important to ...

and the soluble negative regulator C4b-binding protein (C4BP) (which inhibits the classical and lectin pathways). Recent structural data have elucidated the molecular mechanisms that are ...

A range of complement proteins and immunogloublins were screened to test if Sapt1 had any proteolytic activity. Sapt1 efficiently cleaved human mannose-binding lectin (MBL) and collectin-11, which are ...

Insect PGRPs are mainly inducers of proteolytic and signalling cascades. Each PGRP domain has one peptidoglycan-binding groove that is specific for muramyl-pentapeptide and that can discriminate ...

A Wyss Institute team has been selected to develop a broad-spectrum antimicrobial therapeutic under a contract from the DARPA-SHIELD program.

Mannose is available as a supplement but is also found naturally in fruits such as cranberries A nutritional supplement may be able to slow the development of some cancers and enhance the effects ...

Mandatory binding arbitration is a proceeding used to settle disagreements between two parties. As the name implies, the parties are required (or mandated) to use an arbiter to hear their ...

Protein Sci. 26, 1080-1085 (2017). Suzuki T, Kajino M, Yanaka S, Zhu T, Yagi H, Satoh T, Yamaguchi T, Kato K. Conformational analysis of a high-mannose-type oligosaccharide displaying glucosyl ...