Because many different genes can be loosely defined as memory-permitting or memory-suppressing, transient changes in gene methylation provide a potential mechanism for temporary recruitment or ...
The mammalian one carbon metabolism provides the methyl groups for all biologic methylation reactions that in turn ... an important regulatory mechanism for homology-dependent gene silencing.
SAM serves as the methyl donor for biological methylation ... The source of the sulfur for the reaction, and the mechanism of its insertion, are still unresolved and are actively debated.