Mouse models have significantly contributed to our understanding of liver fibrosis and its potential for regression. While no model perfectly replicates human disease, these experimental systems ...

Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease. Current efforts to ...

Liver-specific SMN1 gene therapy both improved liver functioning, and also reduced other SMA-like symptoms in a mouse model ...

This review provides a detailed examination of experimental mouse models used to study liver fibrosis regression, both in ...

Researchers have identified a new axis of host defense by studying what happens during enteric infection -- a term that encompasses all types of intestinal infections including so called 'stomach flu.

A n antibody called bFKB1 improves liver disease and atherosclerosis in a mouse model of metabolic dysfunction-associated ...

Explore how E-selectin-targeted polymer-doxorubicin therapy induces regression in colorectal liver metastases.

RTY-694 increased protein levels and function of ABCB4 and BSEP in primary hepatocytes, two transporters that play a key role in bile composition ...

Subset analysis of FASCINATE-2 Phase 2 trial demonstrated denifanstat improved fibrosis in difficult-to-treat MASH patientsBoth artificial ...