The protein that is coded for by the mutant allele doesn’t function correctly and can distort the shape of red blood cells. If a person has two copies of the mutant allele in their body cells ...

capable of being ligated to either the wild-type or mutant locus, with precise base stacking continuity with the 5´ end of the P1 probe. An allele-specific base was located at a 3´-hydroxyl ...