Additional experiments used GnT-IVa enzymes with different N-glycans capable of ... is the first case of a specific glycan self-regulating its own biosynthesis," said Kizuka.

Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics.

The reversible attachment of an activated form of N-acetylglucosamine (UDP-GlcNAc) acts as a molecular switch between the growth and arrest of cells, establishing a new role for cell surface glycans.

In this study, researchers used high-performance liquid chromatography (HPLC) to characterize mucin O-glycans and food-derived N-glycans, focusing on their structural attributes and effects on A.

Metabolomics studies offer an alternative approach to study N - or O-linked ... genome to carbohydrate biosynthesis. Studies typically generate deletions of individual glycan-associated ...