Natural killer cells that live in the lungs can rapidly respond to a sugar rush, making them especially effective
almost as if they are primed and waiting for a sugar rush to activate them. This metabolic readiness highlights a specialized ...
Using the body’s own defences to fight cancer: new research offers a clue from COVID-19
New research shows white blood cells activated by COVID-19 may have cancer-fighting abilities, offering hope for future ...
Too Old to Operate7d
Inhibition of Cbl-b restores effector functions of human intratumoral NK cells.
T cell-based immunotherapies including immune checkpoint blockade and chimeric antigen receptor T cells can induce durable responses in patients with cancer. However, clinical efficacy is limited due ...
News Medical1y
Potentiated CD16 activated ADCC CAR-NK cells
The types and characteristics of FcγRs. Source: Sino Biological Inc. To mediate antibody-dependent cellular cytotoxicity (ADCC), NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA).
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Potentiating CD16-Activated ADCC in CAR-NK Cell Therapy
NK cells recognize cell-bound antibodies via CD16A (FcγRIIIA) to mediate antibody-dependent cellular cytotoxicity (ADCC). Potentiating therapeutic mAb-mediated CD16 activation of NK cells is an ...