A meaningful rank of NSAIDs in terms of inhibition of COX should take into account the complexities inherent in biochemical systems, including the mechanism of catalysis of the endogenous substrate.

All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...

The mechanism of action of indomethacin, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Use lowest effective dose for shortest ...

This article explains the types, effects, and precautions of OTC pain relievers, helping users choose the right one for their ...

Excursions permitted to 15°C to 30°C (59°F to 86°F). The mechanism of action of diclofenac, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase ...

This also makes it a suitable option for those with a history of stomach ulcers or sensitivities to other NSAIDs. The drug's ...