▎药明康德内容团队编辑  利用自身免疫系统对抗肿瘤的免疫疗法，已经在过去十年间极大地改写了癌症治疗的格局。不过，肿瘤免疫疗法也面临着一大难题，那就是相当一部分患者无法从中获益，或是很容易产生耐药性。而限制肿瘤免疫疗法的一个因素是，肿瘤免疫微环境（TI ...

NK 3.3 cells are CD3-, CD4-, CD8-, CD2+, CD16+, CD56+. They are capable of strong NK cell lysis of sensitive target cells. NK 3.3 cells have been shown to kill by both perforin/granzyme mediated ...

Human NK cells are a subset of peripheral blood lymphocytes defined by the expression of CD56 or CD16 and the absence of the T-cell receptor CD3. NK cells comprise of 10–15% of the lymphocyte ...

In addition, the association of CD3 with the TCR–peptide–MHC complex transmits the activation signal to intracellular signalling molecules to initiate a signalling cascade in the T cell.

Our other products for T cell activation and expansion: GMP Grade anti-CD3 Antibody, GMP Grade Anti-human CD3/CD28 magnetic beads, GMP Grade IL-2, IL-7, IL-15, IL-21, etc. 2. Enhance NK cell ...

By combining these TCRs with different components of the immune system such as T cells, natural killer (NK) cells or a CD3 complex (TCE, T cell engager), highly specific, sensitive and safe modalities ...