A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...

The Notch signaling pathway is central to a wide array of developmental processes in a number of organ systems, including hematopoiesis, somitogenesis, vasculogenesis, and neurogenesis.

A closer look at the gene expression profiles in these atrophied muscle cells showed that they all exhibited an upregulation in the Notch signaling pathway. This pathway is essential for cell ...

The scientists found how this summons non-native monocytes to the liver, and how Notch signaling transforms them into ...

Specifically, we would like to understand how these glycosyltransferases regulate the activity of the Notch signaling pathway in a dosage-sensitive and tissue-specific manner. We have reported a mouse ...