This article from Thermo Scientific Data Visualization Solutions explains how Amira Software was able to solve a 60-year ...

However, mouse oocytes derived from genetically defined ... especially after postimplantation stages 5. Blastocysts derived from nuclear transfer using ES cells exhibit a high rate of term ...

mtDNA replication ceases prior to fertilization of the oocyte and is not re-initiated until at least the late blastocyst stage 41. Failure to initiate this event results in early embryonic death ...