Researchers at University of Tsukuba revealed that administering naldemedine, which is a constipation medication, alongside opioids effectively prevents opioid-induced constipation, thereby ...

According to a 2023 article published by StatPearls, anywhere from 40% to 60% of opioid users can experience opioid-induced constipation. This is primarily because opioids inhibit the movement of ...

Exclusion criteria included fecal impaction, mechanical bowel obstruction, constipation not attributed to postprocedure opioid use, calculated creatinine clearance less than 50 mL/min, and ...

Within 4 hours of the first dose, defecation occurred in 48% of methylnaltrexone patients and in 15% of the placebo patients. Constipation is common among people who take opioids chronically.

Stomachaches and pains can occur for various reasons, including constipation, gas, and heartburn. In some cases, ...

Rizmoic is a once-daily 200-microgram oral tablet for the treatment of opioid induced constipation (OIC) in adult patients previously treated with a laxative. Shionogi received EU marketing ...

This is an oral tablet that treats opioid-induced constipation, a common side effect of using opioid pain medications. Methylnaltrexone is a peripheral opioid receptor antagonist that protects ...

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results From an International Multicenter Study Preventive use of naldemedine for ...

Rizmoic is a once-daily 200-microgram oral tablet for the treatment of opioid induced constipation (OIC) in adult patients previously treated with a laxative. Shionogi received EU marketing ...

The secondary end points included frequency of spontaneous bowel movements (SBM), quality of life (QOL), and frequency of opioid-induced nausea and vomiting (OINV). Of the 103 patients assessed for ...