Researchers at University of Tsukuba revealed that administering naldemedine, which is a constipation medication, alongside opioids effectively prevents opioid-induced constipation, thereby ...

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results From an International Multicenter Study Preventive use of naldemedine for ...

Within 4 hours of the first dose, defecation occurred in 48% of methylnaltrexone patients and in 15% of the placebo patients. Constipation is common among people who take opioids chronically.

Exclusion criteria included fecal impaction, mechanical bowel obstruction, constipation not attributed to postprocedure opioid use, calculated creatinine clearance less than 50 mL/min, and ...

The secondary end points included frequency of spontaneous bowel movements (SBM), quality of life (QOL), and frequency of opioid-induced nausea and vomiting (OINV). Of the 103 patients assessed for ...

Rizmoic is a once-daily 200-microgram oral tablet for the treatment of opioid induced constipation (OIC) in adult patients previously treated with a laxative. Shionogi received EU marketing ...

Rizmoic is a once-daily 200-microgram oral tablet for the treatment of opioid induced constipation (OIC) in adult patients previously treated with a laxative. Shionogi received EU marketing ...

These alkaloids activate opioid receptors in the brain ... one can have varying levels of tolerance towards kratom-induced ...

This is an oral tablet that treats opioid-induced constipation, a common side effect of using opioid pain medications. Methylnaltrexone is a peripheral opioid receptor antagonist that protects ...

The city of St. Petersburg, Florida, is allocating $1 million from an opioid settlement to nonprofit organizations working to address the opioid crisis through treatment and recovery support services.

Opioid overdose deaths have dropped to the lowest they have been in three years, new estimates from the Centers for Disease Control and Prevention suggest, in the wake of a record surge of ...