may be an appropriate response to inadequately treated pain Opioid-induced hyperalgesia A neuroplastic change in pain perception resulting in an increase in pain sensitivity to painful stimuli ...

Unfortunately, in up to 30–40% of patients that chronically consume opioids, opioid-induced hyperalgesia occurs. [59] This condition refers to a generalized and increasing pain sensitivity that ...

Opioid-induced hyperalgesia (OIH) and allodynia; consider decreasing dose of current opioid or opioid rotation if OIH is suspected. COPD, cor pulmonale, decreased respiratory reserve, hypoxia ...

Opioid-induced hyperalgesia (OIH) and allodynia; consider decreasing dose of current opioid or opioid rotation if OIH is suspected. COPD, cor pulmonale, decreased respiratory reserve, hypoxia ...

The Doyle lab studies the pathophysiological and signaling mechanisms (e.g. glutamatergic signaling, neuroinflammation and nitro-oxidative stress) common to the development of cognitive impairment, ...

A 60-second ad was devoted to opioid-induced constipation. The advert - paid for by AstraZeneca - advised sufferers to visit their doctor and "ask about prescription treatment options".

This is an oral tablet that treats opioid-induced constipation, a common side effect of using opioid pain medications. Methylnaltrexone is a peripheral opioid receptor antagonist that protects ...

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results From an International Multicenter Study Preventive use of naldemedine for ...

Rizmoic is a once-daily 200-microgram oral tablet for the treatment of opioid induced constipation (OIC) in adult patients previously treated with a laxative. Shionogi received EU marketing ...

The secondary end points included frequency of spontaneous bowel movements (SBM), quality of life (QOL), and frequency of opioid-induced nausea and vomiting (OINV). Of the 103 patients assessed for ...