p53 lies at the hub of a vast signalling network. Polymorphisms in upstream activators, repressors or downstream effectors of p53 might individually modulate cancer risk or interact with ...

近日，天津医科大学总医院谢松波教授、钟殿胜教授联合团队在Science Bulletin发表了题为“An engineered DNA aptamer-based PROTAC for precise therapy of p53-R175H ...

With respect to a possible predictive or prognostic utility of altered hedgehog network gene expression, expression of PTCH1 or SMO did not correlate with histological grade (DCIS only) or with ...