To purify the amplification products, extract each reaction once with phenol/chloroform/isoamyl alcohol (25: 24:1, v/v/v) and then with chloroform/isoamyl alcohol (29:1, v/v) and recover the DNA ...

This important manuscript provides insights into the competition between Splicing Factor 1 (SF1) and Quaking (QKI) for binding at the ACUAA branch point sequence in a model intron, regulating exon ...

This important study explores the interplay between gene dosage and gene mutations in the evolution of antibiotic resistance. The authors provide solid evidence to connect proteostasis with gene ...