Rab proteins achieve this by reversibly associating with lipid membranes through a process that is known as Rab membrane cycling. Active GTP-bound prenylated Rab proteins are present in membranes.

J Biol Chem. 2008 Aug 8;283(32):22076-88. doi: 10.1074/jbc.M803901200. Epub 2008 Jun 4. Resh MD. Palmitoylation of ligands, receptors, and intracellular signaling molecules. Sci STKE. 2006 Oct 31;2006 ...