Once again, alternatives to combat pain and fever were sought ... of cyclooxygenase (COX), enzymes that act early in the pathways of prostaglandin synthesis. So far, three COX enyzymes have ...

These prostaglandins cause the tissue to swell. They also amplify the electrical signal coming from the nerves. Basically, they increase the pain you feel. NSAIDs work on a chemical level.

By examining keratinocytes from donors of different ethnicities and ages, the researchers identified the PTGS2/PGE2/EP4 pathway as a key driver of this escape process. The researchers show that ...

A recent study reveals a genetic connection between depression and menstrual pain, suggesting depression may increase the ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...

When the IOP is abnormally elevated, it is usually because of an increase in resistance in the trabecular outflow pathway. Endogenous prostaglandins (PGs) and their receptors are found in the ...

Pain is the stimulation of nerve endings, either due to swelling or release of prostaglandins, and painkillers work on the same pathway to the pain. Dr Mary Joan McLeod 2. Painkillers follow the ...

Endogenous prostaglandins (PGs) and their receptors are found in the aqueous humor drainage pathways. Endogenous PGs biochemically regulate the matrix metalloproteinases and tissue inhibitors of ...