The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...

In “My Own Country,” a 1994 memoir, Dr. Abraham Verghese, an infectious disease physician, recounts the story of a young man ...

Nucleoside reverse transcriptase inhibitor; PI: Protease inhibitor; PK: Pharmacokinetics; RPV: Rilpivirine. Data taken from [10,33–38]. Blake Max's spouse is employed as a regional medical ...

Investigators from Duke University hypothesized that hirudin-like protease inhibitors could be generated by linking exosite-binding aptamers with small-molecule active site inhibitors, thus generating ...

Two additional M pro inhibitors, Ensitrelvir (ETV ... "Assessing the Inhibition Efficacy of Clinical Drugs Against the Main Proteases of SARS-CoV-2 Variants and Other Coronaviruses," provides ...

These viral proteases are critical for virion assemble and are often targeted for drug design. A famous example is HIV protease inhibitors. Viral proteases utilize many different catalytic mechanisms ...

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The single and multiple-dose escalation trial will involve 64 participants, including both healthy adults and AATD patients ...