The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...

The MMPs were the first protease targets seriously considered for combating cancer because of their role in extracellular matrix degradation. Several MMP inhibitors, which can be generally divided ...

Food indeed contributes to the pharmacokinetic variability of protease inhibitors (PIs). [1] The exact mechanism(s) are poorly understood. As determined by measuring the area under the ...

Historically, most people started HIV treatment with two drugs from the NRTI class combined with either one NNRTI, one protease inhibitor or one integrase inhibitor – hence, ‘triple therapy’.

Two additional M pro inhibitors, Ensitrelvir (ETV ... "Assessing the Inhibition Efficacy of Clinical Drugs Against the Main Proteases of SARS-CoV-2 Variants and Other Coronaviruses," provides ...

In “My Own Country,” a 1994 memoir, Dr. Abraham Verghese, an infectious disease physician, recounts the story of a young man ...

Investigators from Duke University hypothesized that hirudin-like protease inhibitors could be generated by linking exosite-binding aptamers with small-molecule active site inhibitors, thus generating ...