The enzyme protein kinase N (PKN) has been implicated in a signaling cascade that causes heart fibroblast activation. A group ...

An increasing number of small-molecule protein kinase inhibitors are being developed and extensively tested for specificity against a panel of human kinases and in animal models of chronic ...

第一篇文章的题目是Role of protein kinase PLK1 in the epigenetic maintenance of centromeres ... 第二篇文章的题目是PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere ...

As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the ...

The enzyme converts heart fibroblasts to myofibroblasts, putting the heart's integrity at risk. Deleting this enzyme reduced ...

Researchers have identified the enzyme PKN as a key factor in heart fibrosis, potentially leading to new treatments for heart ...

As the TrkB/MAP kinase cascade is probably limited to that population ... glass chromatography as described 32. Equal amounts of protein from control and BDNF-treated synaptosomal samples were ...

The transduction of extracellular signals across the membrane to initiate complex cascades of molecular events regulates numerous ... We are also actively investigating the regulation of Syk tyrosine ...

A team at Nagoya University Graduate School of Medicine has found that the enzyme protein kinase N (PKN) plays a role in ...

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...

One of the things that makes brains so incredibly difficult to understand is their ability to adjust and adapt. Our learning ...

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