Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, ...

Novel macrocyclic heteroaryl derivatives acting as non-receptor tyrosine-protein kinase TYK2 and/or JAK1 and/or JAK2 inhibitors have been reported in a Hangzhou Highlightll Pharmaceutical Co. Ltd.

In the study, "Melatonin receptor 1A variants as genetic cause ... and mitogen-activated protein kinase pathways, which triggered osteoblast senescence and bone loss. The findings point to a ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...

Aberrant activation of the Src family of tyrosine kinases has been implicated in ... of combination therapy with epidermal growth factor receptor inhibition and cytotoxic chemotherapy.

Targeted therapy revolutionized cancer treatment, with gene fusions leading the way when the FDA approved imatinib in 2001 to ...

This bioinformatics-assisted review describes key biological elements of known pathways, such as the forkhead box protein ...