Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called ...

However, in the half-century since the structure of DNA was first elaborated, scientists have learned that RNA does much more than simply play a role in protein synthesis. For example, many types ...

My laboratory studies the regulatory and structural roles of mRNAs in the cytoplasm. Specifically, we investigate how 3′UTRs regulate protein functions in a manner that is independent of protein ...

This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).

The process of ribosome biogenesis involves the transcription of rRNA precursors ... which are characterized by defects in ribosome function and protein synthesis. rRNA is one of the most highly ...