引言近年来，RNA生物学的重要性愈发凸显，特别是在新型疫苗和基因调控技术的突破中，RNA分子展现了前所未有的潜力。然而，RNA的复杂三维结构依然是生命科学领域中最具挑战性的问题之一。其灵活的折叠和多样的构象意味着单凭实验手段难以全面揭示这些分子背后的 ...

引言细胞周期是生物生命过程中一个至关重要的过程，涉及一系列的分裂与生长事件。从细胞分裂到准备再次分裂，这个周期包括多个关键阶段，如G1、S、G2和M期。研究人员一直在尝试揭示这些阶段中的基因表达动态，而RNA速度（RNA ...

To tackle this question, the researchers devised a model simulating basic RNA molecules devoid of enzymatic activity. Within ...

【导读】 就在刚刚，AI设计DNA、RNA和蛋白质序列的能力再获得颠覆性突破，研究登上Science封面。Evo模型能以无与伦比的准确性，解码和设计从分子到基因组规模的对象了，合成生物学的工作方式，从此或将彻底颠覆。

By Vijay Kumar MalesuRhoFold+ delivers a leap in RNA 3D structure prediction, combining speed and accuracy to tackle data ...

Conventional targeted RNA-seq methods often require labor-intensive ... It also integrates an EM-based model to achieve unbiased transcriptome quantification using both fully sequenced targets ...

Evo is a large language model that is not trained on words but on the genomes of millions of microbes. It can accurately ...