What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

Then the RNA binding protein communicates to the splicing machinery to include ... At the posttranscriptional level, nonsense mediated decay (NMD) is a process closely linked to alternative splicing ...

这一研究成果公布在Cancer Cell杂志上，由MD安德森癌症中心生物信息学和计算生物学副教授梁晗博士以及Gordon Mills博士领导完成，梁晗博士研究组研究兴趣包括开发生物信息学工具，更好地分析癌症基因组数据，泛癌症基因组分析，RNA编辑和癌细胞的进化过程。

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information ... These molecules function to process rRNA molecules, often resulting in the ...

In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

该研究首次揭示了糖RNA在分子结构和生物学基础方面的信息，为糖RNA的存在提供了直接证据，并为后续RNA糖基化的生物合成以及生物功能研究奠定了 ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

If the nascent RNA is destroyed before it gets fully ... help develop new treatments that leverage the alternative splicing-NMD process. Drug molecules could be designed to decrease the amount ...

U1 snRNP interactions in Arabidopsis highlight its dual role in splicing and mRNA regulation, essential for maintaining transcript integrity and growth.

RNA-sequencing has become a cornerstone in ... One area of increasing interest is alternative splicing, a process that allows a single gene to produce multiple transcript variants and thus protein ...

In this process, adenosine deaminases acting on RNA (ADARs) convert adenosine (A) to inosine (I) by hydrolytic deamination. Since inosine is interpreted as guanosine (G) by the cellular machinery, ...