Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

After all, the cell must repeat its whole genetic material, including billions of genetic letters, before it can divide. Read ...

This RNA-containing complex can then inhibit transcription of an mRNA molecule that has a sequence complementary to its RNA component. Inside the eukaryotic nucleus, the nucleolus is the structure ...

此外，对于阿尔茨海默病、亨廷顿舞蹈症等神经系统疾病患者来说，当针对他们的核斑点加以研究，就能发现其与正常人在 RNA 剪接和核斑点定位上的差异，从而助力于通过干预 RNA 剪接来治疗神经疾病。 同时，ARTR-seq ...

Researchers from The University of Texas at Austin discovered important information about an enzyme that can protect cells ...

Efficient removal of rRNA is critical to enable cost-effective sequencing of RNA samples. Depletion of rRNA from total RNA before library construction can result in the loss of rare or low-abundance ...

Using CRISPR technology that targets RNA instead of DNA, researchers at New York University and the New York ... "With Cas13, ...

Conventional targeted RNA-seq methods often require labor-intensive pre-sequencing enrichment steps, which can compromise comprehensive transcriptome profiling and limit their broader applications.

A recent study leveraging single-cell RNA sequencing (scRNA-seq) has uncovered vital molecular mechanisms underlying NB's ...

Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, United States This important study employed multiple orthogonal techniques and ...