直到现在,线粒体中tRNA成熟的确切过程还没有被很好地理解。 “我们的研究在分子水平上揭示了线粒体RNase Z复合物如何识别和处理tRNA分子,”该研究的第一作者Genís Valentín Gesé 说。“通过使用先进的低温电子显微镜,我们已经能够看到这种复合物的作用 ...
Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have made a major discovery in how human ...
Ribonuclease (RNase) protection is a common and powerful technique used for the analysis of RNA levels. RNA probes used in RNase protection are commonly produced by in vitro transcription of DNA ...
Up until today, nothing was known about the precise mechanism of tRNA maturation in mitochondria. Our study reveals, at a ...