These findings could pave the way for new treatment approaches for cancers driven by RAS mutations. Researchers at the ...

The RAS superfamily of GTPases includes five major ... that demonstrate selectivity for monomeric versus heterotrimeric G proteins (such as GGTI-DU40) is another particularly promising therapeutic ...

Researchers have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their well-known role in signaling at the cell surface. Mutant RAS, they ...