The first CF rat model, CFTR tm1sage (termed CFTR-/- or KO), was designed in collaboration with SAGE (now Horizon Discovery) and subsequently characterized at UAB and distributed to the CF community.
The Newcells aProximateTM near-physiological kidney transporter model provides cross-species comparison of drug handling.
University of Wisconsin–Madison researchers targeting a group of hereditary neurodegenerative diseases have found success ...
In a new study, researchers have developed a comprehensive in silico model of the rat hippocampal CA1 region. This model is ...
Low-extremity ischemic disease is a common complication in diabetic patients, leading to reduced quality of life and potential amputation. This study investigated the therapeutic effect of spinal cord ...
Five groups are now working together to assemble, annotate and release an updated version of the rat genome. As the prevailing model for physiology, complex disease and pharmacological studies ...
UW–Madison researchers used gene therapy to prevent hereditary spastic paraplegia (HSP) in a rat model, introducing a healthy ...