block the effects of the renin enzyme, relaxing blood vessels and allowing blood to flow more easily. They are widely used as first-line medications for hypertension (high blood pressure).
A brief summary will suffice. Renin is a proteolytic enzyme normally released from the kidney under the stimulus of a decrease in BP or extracellular fluid volume as sensed by special receptors.
Scientists have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood. The finding could open the door to ...
[32] Experimental data in sheep treated with angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARBs) alone, or in combination after myocardial infarction revealed ...
The class of drugs, known as renin–angiotensin system (RAS) inhibitors, block the effects of the renin enzyme, relaxing blood vessels and allowing blood to flow more easily. They are widely used as ...