A surrogate test that may have clinical relevance is the duration of inhibition at 5-HT 3 receptors located on cutaneous afferent neurons. Intradermal injection of serotonin produces a flare ...

The theoretical basis for and clinical experience with using oral serotonin type 3 (5-HT 3)-receptor antagonists for preventing chemotherapy-induced emesis are discussed. Evidence supports the ...

A second study comparing telcagepant with rizatriptan (Maxalt; Merck) — a drug from the triptan class of serotonin receptor agonists, which are currently the standard of care for migraine ...

Medically reviewed by Scott Zashin, MD Serotonin is a neurotransmitter, a chemical messenger that helps with regulating mood.