The sinus node – sometimes known as the sinoatrial node - generates electrical impulses which cause the heart to beat. It consists of a cluster of cells in the upper part of the right upper chamber of ...

Abnormally slow heart rates result from breakdowns in two principal areas of the heart. First, the sinoatrial, or SA, node sets your “resting” heart rate, usually somewhere between 60 and 100 beats ...

Researchers discovered that gene deserts, non-coding DNA regions, regulate heart and embryo development through enhancer ...

A healthy heart has an initial action impulse generated in the sinoatrial node and carried through the heart's upper chambers or atria. The impulse then moves down the internodal atrial pathways ...

There are several key areas that conduct electrical signals through the heart – the sinoatrial node, atrioventricular node, and bundle branches all work like players in an orchestra to keep a ...

Conduction system abnormalities and sudden death Conduction system abnormalities have been described in a number of SCDs in athletes, usually due to premature aging, sclerosis of the left side of the ...

Ivabradine is a selective inhibitor of the I f ion channel found in cardiac pacemaker cells of the sinoatrial node. The drug reduces heart rate at rest and during exercise in patients in sinus ...

Typically, the signal for your heartbeat starts in the right atrium in the sinoatrial node and travels to both the left and right ventricles, allowing your heart to coordinate its rhythm in your ...

Figure 1: Desensitization of the acetylcholine response in the sinoatrial pacemaker cell of the heart. Figure 2: Diagram showing the crosstalk between the M2 and M3 muscarinic acetylcholine ...

POPDC1 variants cause atrioventricular node dysfunction and arrhythmogenic changes in cardiac electrophysiology and intracellular calcium handling in zebrafish. Genes. 2024; 15:280. Stoyek MR*, ...