Over 2 decades ago, the aldosterone antagonist eplerenone proved beneficial after MI complicated by left ventricular ...

Spironolactone was initiated at a dose of 25 mg daily at the first ambulatory blood pressure monitoring and titrated to 50 mg or 100 mg daily after office-based assessment of blood pressure at ...

It has some similarities to the potassium-sparing diuretic spironolactone ... treatment is initiated at 25 mg once daily and titrated to a target of 50 mg once daily within 4 weeks.