Another class of drugs that exploit a natural mechanism to decrease the ability of CaV2.2 to respond to pain signalling are the opioid drugs, like morphine and heroin. While very effective at ...

Another class of drugs that exploit a natural mechanism to decrease the ability of CaV2.2 to respond to pain signalling are the opioid drugs, like morphine and heroin. While very effective at ...

This knowledge can be used to develop drugs for chronic pain that are more effective and have fewer side effects. When the electrical signal reaches the end of one nerve cell, it is converted into ...

Another class of drugs that exploit a natural mechanism to decrease the ability of CaV2.2 to respond to pain signalling are the opioid drugs, like morphine and heroin. While very effective at ...

researchers must understand the details of what happens at the molecular level when pain signals are converted from one form to another. When the electrical signal reaches the end of one nerve ...

The researchers are also harnessing their new understanding of the pain signaling complex, determining the sites at which nerve growth factor, TrkA, and NRP1 interact, and generating peptides that ...