DRB1*11:01 was associated with an increased risk of anti-HMGCR myopathy. This study, therefore, suggests a mechanistic link between statin exposure, increased HMGCR expression and the potential ...

【导读】科学界尚不清楚血脂是否与结直肠癌（CRC）风险有因果关系。2024年11月23日，英国帝国理工学院公共卫生学院在期刊《British Journal of Cancer》上发表了题为“Associations of blood lipids ...

Important genes involved in the lipid-lowering response to statin therapy include the HMGCR and APOE genes. However, those results are equivocal and further studies are needed to explore the role ...

“It’s incredibly rare.” Myositis in general affects 50,000 to 75,000 people in the U.S., but the statin-triggered type Furlan had — called HMGCR necrotizing myopathy — is seen in only ...