They are fairly expensive (three—naratriptan, rizatriptan, and sumatriptan—are now available as generics), ranging from $12 to $46 per pill. The nasal spray and injectable forms cost more.
The apparent volume of distribution is 2.7 L/kg. The elimination half-life of sumatriptan administered as a nasal spray is approximately 2 hours, similar to the half-life seen after subcutaneous ...
following oral dosing with 100 mg of sumatriptan. This compares with a Cmax of 5 and 16 ng/mL following dosing with a 5- and 20-mg intranasal dose, respectively. The bioavailability is ...
Sumatriptan Nasal spray was approved in 2019 February by the US FDA. When should Sumatriptan not be taken? (Contraindications) Contraindicated in patient with prior heart attack and other heart ...
OptiNose's novel Breath Powered intranasal delivery system contains a low-dose sumatriptan powder to treat acute migraine. Under terms of the agreement, as well as the upfront $20 million payment ...
This is where Tonix's Tosymra steps in. A nasal spray version of sumatriptan, Tosymra is designed to deliver the same rapid relief as Zembrace SymTouch but using Intravail® technology, which ...