The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

She also had numerous small subcutaneous tophi in her hands. The patient was intolerant to allopurinol and had mild renal insufficiency attributed to uric-acid nephrolithiasis and interstitial ...

He had a prior history of coronary heart disease, high-grade ischemic cardiomyopathy, chronic renal failure, and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia ...