Topiramate, an antiepileptic drug with potential mechanisms of action including sodium channel blockade, inhibition of glutamate receptors, and enhancement of γ-aminobutyric acid (GABA ...

Get detailed information on Topiramate, including pronunciation ... When used alone, the starting dose is 25 mg/ night taken orally. The dose may be increased after 1 week to a maximum of 400 ...

weight losses of 4.5% and 6.5% were achieved in patients who received 96 mg and 192 mg topiramate daily, respectively, compared with 1.7% in placebo-treated patients (P <0.001 for both comparisons).

A combination of metformin and topiramate along with a low-calorie diet was an effective, low-cost weight loss strategy in women with polycystic ovary syndrome.

One study organized 385 people into groups by BMI and then were randomized to receive a placebo (nontherapeutic substance) or ...